Histones Rule!: The FASEB Conference on Chromatin and Transcription. July 7–12, 2001
نویسندگان
چکیده
منابع مشابه
Histones Rule!: The FASEB Conference on Chromatin and Transcription. July 7–12, 2001
1064413 that remodeling complexes affect DNA twist (rotation), writhe (the path of the DNA) or both. But adding H1 to in vitro reactions shuts down remodeling. Perhaps, said Peterson, this can be explained by H1’s ability to prevent changes in DNA topology. H1 binds to DNA as it enters and exits the nucleosome, thus locking the DNA in place. But now Peterson has found that phosphorylation by cy...
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15 صفحه اولChromatin: Hanging on to histones
The core histones have long been known to have an important role in the packaging of DNA into nucleosomes. Today, nucleosome assembly is recognized as an integral component of both transcriptional activation and repression [1]. Transcriptional control is mediated through the assembly of extensive nucleoprotein structures containing both conventional transcription factors and architectural facto...
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Patrick Cramer is a professor of Biochemistry at the Ludwig Maximilians University of Munich, Germany, and head of the Gene Center Munich. He is a structural biologist who has contributed to our understanding of the structure and function of RNAP II from yeast and its associated factors. In a recent study, his laboratory described the structure of RNAP II in complex with the initiation factor T...
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ژورنال
عنوان ژورنال: Journal of Cell Biology
سال: 2001
ISSN: 1540-8140,0021-9525
DOI: 10.1083/jcb1545mr